Journal: Human reproduction (Oxford, England)

Article Title: Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample.

doi: 10.1093/humrep/dem182

Figure Lengend Snippet: Figure 1: Single-nucleotide polymorphisms (SNPs) rs1800630 (-863A/C) genotyped in 958 endometriosis cases and 959 controls using Seque- nom MassARRAY platform (a) Genotypes for rs1800630 (known as -863C/A) were not consistent with Hardy–Weinberg equilibrium, (b) the assay showed good clusters and mass spectra and (c) the sequence of rs1800630 where arrows indicate positions of two neighbouring variants located adjacent to rs1800630 and in the site of the extension primer

Article Snippet: In the Japanese studies, Asghar et al. (2004) found the TNF gene promoter SNP -1031T/C (rs1799964) was associated with stage IV endometriosis comprising 130 cases and 185 controls, whereas Teramoto et al. (2004) found a haplotype defined Figure 1: Single-nucleotide polymorphisms (SNPs) rs1800630 (-863A/C) genotyped in 958 endometriosis cases and 959 controls using Sequenom MassARRAY platform (a) Genotypes for rs1800630 (known as -863C/A) were not consistent with Hardy–Weinberg equilibrium, (b) the assay showed good clusters and mass spectra and (c) the sequence of rs1800630 where arrows indicate positions of two neighbouring variants located adjacent to rs1800630 and in the site of the extension primer D ow nloaded from https://academ ic.oup.com /hum rep/article/22/9/2389/609285 by guest on 04 August 2024 by SNPs -1031T/C, -863C/A and -857C/T (rs1799964, rs1800630 and rs1799724) was associated with endometriosis susceptibility in 123 endometriosis cases and 165 healthy con- trols.

Techniques: Sequencing